N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE - Names and Identifiers
N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE - Physico-chemical Properties
Molecular Formula | C15H14N2O4S
|
Molar Mass | 318.35 |
Density | 1.427±0.06 g/cm3(Predicted) |
Melting Point | 142 - 145°C |
Appearance | Form Solid, color Off-White to Pale Orange |
pKa | 8.31±0.10(Predicted) |
Storage Condition | Amber Vial, Refrigerator, Under inert atmosphere |
Stability | Light Sensitive |
Physical and Chemical Properties | Bioactive Belinostat (PXD101, NSC726630, PX-105684) is a new HDAC inhibitor with IC50 of 27 nM in cell-free test, which is active against Cisplatin-resistant tumors. Belinostat (PXD101) can induce autophagy. |
Use | A Novel HDAC Inhibitor |
N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE - Risk and Safety
N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE - Introduction
Belinostat (PXD101) is a new HDAC inhibitor with IC50 of 27 nM, which is effective against Cisplatin-resistant tumors.
Last Update:2022-10-16 17:30:57